SCHEMBL24782874

SCHEMBL24782874

c1ccc2c(c1)Oc1cccc3c(-c4c5ccccc5c(-c5ccc6ccccc6c5)c5cc(-c6ccc7c(-c8ccccc8-c8ccc9ccccc9c8)c8ccccc8c(-c8ccc9c%10c(cccc8%10)Oc8ccccc8-9)c7c6)ccc45)ccc-2c13

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
MAPK1 P28482 1/20 0.43
ATM Q13315 1/20 0.43
GPR84 Q9NQS5 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
GSTP1 P09211 1/20 0.32
PRKDC P78527 1/20 0.31
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
SOS1 Q07889 1/20 0.31
HIF1A Q16665 1/20 0.31
ANPEP P15144 1/20 0.30
PDE9A O76083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16558378 0.94 MAPK1 (0.48) KDM4EMAPK1ATMGPR84HDAC4
SCHEMBL16558366 0.93 MAPK1 (0.47) KDM4EMAPK1ATMGPR84HDAC4
SCHEMBL16558377 0.93 MAPK1 (0.47) KDM4EMAPK1ATMGPR84HDAC4
SCHEMBL23109599 0.93 MAPK1 (0.49) KDM4EMAPK1ATMGPR84HDAC4
SCHEMBL16558382 0.92 MAPK1 (0.48) KDM4EMAPK1ATMGPR84HDAC4
SCHEMBL22971822 0.92 MAPK1 (0.48) KDM4EMAPK1ATMGPR84HDAC4
SCHEMBL23109668 0.92 MAPK1 (0.50) KDM4EMAPK1ATMGPR84HDAC4
SCHEMBL16558376 0.91 MAPK1 (0.47) KDM4EMAPK1ATMGPR84TSHR
SCHEMBL24782487 0.91 MAPK1 (0.46) KDM4EMAPK1ATMGPR84HDAC4
SCHEMBL23109596 0.91 MAPK1 (0.47) KDM4EMAPK1ATMGPR84HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-01-18 US disclosed
US-20220393113-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE EED, EML4, ESR1 KDM4E 494/4885MAPK1 2256/4885ATM 2500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.