Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 3/20 | 1.00 |
| ▸ | CYP2B6 | P20813 | 3/20 | 1.00 |
| ▸ | SCD5 | Q86SK9 | 16/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | SCD | O00767 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29616541 | 1.00 | CYP2C8 (1.00) | CYP2C8CYP2B6SCD5CYP2C9CYP2C19 | |
| SCHEMBL21523623 | 0.91 | SCD5 (1.00) | CYP2C8CYP2B6SCD5CYP2C9CYP2C19 | |
| SCHEMBL22619737 | 0.87 | CYP2C8 (0.83) | CYP2C8CYP2B6SCD5CYP2C9CYP2C19 | |
| SCHEMBL21523801 | 0.86 | SCD5 (1.00) | CYP2C8CYP2B6SCD5SCDALDH1A1 | |
| SCHEMBL21523680 | 0.86 | SCD5 (1.00) | CYP2C8CYP2B6SCD5SCDALDH1A1 | |
| SCHEMBL21523700 | 0.86 | SCD5 (1.00) | CYP2C8CYP2B6SCD5SCDALDH1A1 | |
| SCHEMBL22619879 | 0.86 | SCD5 (0.87) | CYP2C8CYP2B6SCD5CYP2C9CYP2C19 | |
| SCHEMBL22619895 | 0.86 | CYP2C8 (0.75) | CYP2C8CYP2B6SCD5CYP2C9CYP2C19 | |
| SCHEMBL22619866 | 0.86 | CYP2C8 (0.75) | CYP2C8CYP2B6SCD5CYP2C9CYP2C19 | |
| SCHEMBL22619686 | 0.85 | CYP2C8 (0.75) | CYP2C8CYP2B6SCD5CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266232-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC LIVER DISEASE AND HEPATOCELLULAR CARCINOMA | Sanford Burnham Prebys Medical Discovery Institute (US) | 2022-12-22 | — | — | WO | disclosed |