SCHEMBL24784331

SCHEMBL24784331

C=C(Cl)CCCCCCCCCBr

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.30
NFKB1 P19838 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16665095 0.88
SCHEMBL27422343 0.74
SCHEMBL28440062 0.74 ALDH1A1 (0.42) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL9121924 0.74
SCHEMBL13120811 0.74 TSHR (0.33) TSHRLMNANFKB1PMP22
SCHEMBL12521498 0.74
SCHEMBL10944101 0.74 ALDH1A1 (0.35) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL8276168 0.74 TSHR (0.33) TSHRLMNANFKB1PMP22
SCHEMBL9862225 0.72
SCHEMBL13859605 0.72 TSHR (0.56) ALDH1A1TSHRLMNANFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022265178-A1 TRAP1 INHIBITOR AND USE THEREOF 주식회사 스마틴바이오 2022-12-22 WO disclosed