Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044746 | 0.74 | KMT2A (0.37) | TRPM8ALDH1A1KMT2AKDM4ETSHR | |
| SCHEMBL3753078 | 0.70 | MGAM (0.43) | ALDH1A1KMT2AHSD17B10L3MBTL1POLB | |
| SCHEMBL19052822 | 0.67 | MGAM (0.36) | ALDH1A1KMT2APOLB | |
| SCHEMBL19052835 | 0.67 | MGAM (0.36) | ALDH1A1KMT2APOLB | |
| SCHEMBL6747298 | 0.65 | MGAM (0.34) | ALDH1A1KMT2APOLB | |
| SCHEMBL26077269 | 0.65 | MGAM (0.40) | ALDH1A1KMT2AL3MBTL1POLB | |
| SCHEMBL24784336 | 0.65 | ALDH1A1 (0.42) | ALDH1A1KMT2AHSD17B10L3MBTL1POLB | |
| SCHEMBL23369740 | 0.64 | EPHX2 (0.41) | ALDH1A1KMT2APOLB | |
| SCHEMBL851434 | 0.64 | GAA (0.43) | ALDH1A1KMT2AL3MBTL1POLB | |
| SCHEMBL1881523 | 0.63 | ALDH1A1 (0.46) | ALDH1A1KMT2AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445749-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2022-12-21 | — | — | EP | disclosed |