Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5589851 | 0.89 | KDM4E (0.40) | TSHRCYP3A4HSD17B10ALDH1A1KDM4E | |
| SCHEMBL25329980 | 0.84 | PTGS1 (0.45) | TSHRALOX5HSD17B10ALDH1A1KDM4E | |
| SCHEMBL25329730 | 0.84 | KDM4E (0.38) | TSHRCYP3A4ALOX5HSD17B10ALDH1A1 | |
| SCHEMBL689246 | 0.82 | ESR1 (0.47) | ALOX5ALDH1A1KDM4EMAPTESR1 | |
| SCHEMBL30356497 | 0.82 | TSHR (0.38) | TSHRCYP3A4HSD17B10ALDH1A1KDM4E | |
| SCHEMBL30367452 | 0.82 | ESR1 (0.47) | ALOX5ALDH1A1KDM4EMAPTESR1 | |
| SCHEMBL28058188 | 0.82 | TSHR (0.46) | TSHRHSD17B10ALDH1A1KDM4EMAPT | |
| SCHEMBL16379032 | 0.80 | TSHR (0.39) | TSHRCYP3A4HSD17B10ALDH1A1KDM4E | |
| SCHEMBL25328532 | 0.80 | TSHR (0.41) | TSHRCYP3A4HSD17B10ALDH1A1KDM4E | |
| Hx-1171 SCHEMBL688955 | 0.80 | ESR1 (0.50) | ALOX5ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12583813-B2 | Polymerization inhibitors | BASF SE (DE) | 2026-03-24 | — | — | US | disclosed |
| CN-118108589-A | Preparation method of vitamin E intermediate 2,3, 5-trimethylbenzoquinone | 浙江新和成药业有限公司 | 2024-05-31 | — | — | CN | disclosed |
| US-20230242472-A1 | POLYMERIZATION INHIBITORS | BASF SE (DE) | 2023-08-03 | — | — | US | disclosed |
| EP-4161892-A1 | POLYMERIZATION INHIBITORS | BASF SE (DE) | 2023-04-12 | — | — | EP | disclosed |
| CN-115697954-A | Polymerization inhibitor | 巴斯夫欧洲公司 | 2023-02-03 | — | — | CN | disclosed |
| WO-2022265178-A1 | TRAP1 INHIBITOR AND USE THEREOF | 주식회사 스마틴바이오 | 2022-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242472-A1 | POLYMERIZATION INHIBITORS | RCE1, CABLES1, DPYD | TSHR 4882/4885CYP3A4 2975/4885ALOX5 1518/4885 |
| US-12583813-B2 | Polymerization inhibitors | PTGS1, PTGER1, POT1 | TSHR 4664/4885CYP3A4 1439/4885ALOX5 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.