Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLI1 | P08151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785151 | 0.82 | MAPT (0.50) | MAPTGRIN2DGRIN3BTHRBGRIN1 | |
| SCHEMBL23459089 | 0.79 | GLI1 (0.36) | GLI1MAPTFPR2SCN9ANOS3 | |
| SCHEMBL28232398 | 0.76 | MAPT (0.38) | GLI1MAPTFPR2SCN9ANOS3 | |
| SCHEMBL14754500 | 0.76 | CCR2 (0.39) | GLI1MAPTFPR2SCN9ANOS3 | |
| SCHEMBL14754502 | 0.76 | CCR2 (0.39) | GLI1MAPTFPR2SCN9ANOS3 | |
| SCHEMBL2916377 | 0.76 | CCR2 (0.39) | GLI1MAPTFPR2SCN9ANOS3 | |
| SCHEMBL7397131 | 0.76 | SCN9A (0.34) | GLI1MAPTFPR2SCN9ANOS3 | |
| SCHEMBL5695525 | 0.76 | CCR2 (0.42) | GLI1MAPTFPR2SCN9A | |
| SCHEMBL18806175 | 0.76 | CCR2 (0.42) | GLI1MAPTFPR2SCN9A | |
| SCHEMBL18820343 | 0.76 | CCR2 (0.42) | GLI1MAPTFPR2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172737-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2022266015-A1 | FUSED HETEROARYL COMPOUNDS USEFUL AS ANTICANCER AGENTS | KUMQUAT BIOSCIENCES INC. (US) | 2022-12-22 | — | — | WO | disclosed |