Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103004 | 1.00 | KDM1A (0.41) | KDM1ACYP1A1CYP1B1GRK6FGFR1 | |
| SCHEMBL24785335 | 0.84 | KDM1A (0.41) | KDM1ACYP1A1CYP1B1GRK6FGFR1 | |
| SCHEMBL25367489 | 0.81 | KDM1A (0.41) | KDM1ACYP1A1CYP1B1GRK6FGFR1 | |
| SCHEMBL30516658 | 0.81 | KDM1A (0.41) | KDM1ACYP1A1CYP1B1GRK6FGFR1 | |
| SCHEMBL24784608 | 0.77 | KDM1A (0.40) | KDM1ACYP1A1CYP1B1GRK6FGFR1 | |
| SCHEMBL30018135 | 0.75 | CYP1A1 (0.55) | KDM1ACYP1A1CYP1B1GRK6LRRK2 | |
| SCHEMBL27859257 | 0.75 | CYP1A1 (0.55) | KDM1ACYP1A1CYP1B1GRK6LRRK2 | |
| SCHEMBL30103132 | 0.75 | KDM1A (0.47) | KDM1ACYP1A1CYP1B1GRK6FGFR1 | |
| SCHEMBL24785377 | 0.75 | KDM1A (0.47) | KDM1ACYP1A1CYP1B1GRK6FGFR1 | |
| SCHEMBL26784179 | 0.74 | ABL1 (0.49) | PGRABCB1ABL1BCRCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257960-A1 | BICYCLIC COMPOUND FOR THE TREATMENT OF EP2 AND EP4 RECEPTOR-MEDIATED DISEASES | 武汉人福创新药物研发中心有限公司 | 2022-12-15 | — | — | WO | disclosed |