Sofalcone

Sofalcone

SCHEMBL24786

CC(C)=CCOc1ccc(/C=C/C(=O)c2ccc(OCC=C(C)C)cc2OCC(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
NR1I2 O75469 1/20 1.00
LMNA P02545 1/20 1.00
PGR P06401 1/20 1.00
ADRB2 P07550 1/20 1.00
ADRB1 P08588 1/20 1.00
ADORA3 P0DMS8 1/20 1.00
HPGD P15428 1/20 1.00
CNR1 P21554 1/20 1.00
TBXA2R P21731 1/20 1.00
SLC6A2 P23975 1/20 1.00
AGTR1 P30556 1/20 1.00
ADRA1A P35348 1/20 1.00
OPRD1 P41143 1/20 1.00
OPRK1 P41145 1/20 1.00
BLM P54132 1/20 1.00
SLC6A3 Q01959 1/20 1.00
ALOX5 P09917 4/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sofalcone SCHEMBL30383975 1.00 MAPT (1.00) MAPTMEN1KMT2ANR1I2LMNA
Sofalcone SCHEMBL40766 1.00 MAPT (1.00) MAPTMEN1KMT2ANR1I2LMNA
Sofalcone SCHEMBL25214686 1.00 MAPT (1.00) MAPTMEN1KMT2ANR1I2LMNA
Sofalcone SCHEMBL29363342 1.00 MAPT (1.00) MAPTMEN1KMT2ANR1I2LMNA
SCHEMBL9364195 0.99 MAPT (0.98) MAPTMEN1KMT2ANR1I2LMNA
Sofalcone SCHEMBL7842101 0.99 MAPT (0.98) MAPTMEN1KMT2ANR1I2LMNA
SCHEMBL9364183 0.99 MAPT (0.98) MAPTMEN1KMT2ANR1I2LMNA
SCHEMBL30382974 0.99 MAPT (0.98) MAPTMEN1KMT2ANR1I2LMNA
Sofalcone SCHEMBL10888696 0.96 MAPT (0.92) MAPTMEN1KMT2ANR1I2LMNA
SCHEMBL9368121 0.94 MAPT (0.89) MAPTMEN1KMT2ANR1I2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12940 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US claimed
WO-2025264604-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2025-12-26 WO claimed
US-20250381110-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME PROCTER & GAMBLE (US) 2025-12-18 US claimed
EP-4580612-A1 USE OF NRF2 ACTIVATORS FOR THE TREATMENT OF CEREBRAL SMALL VESSEL DISEASE Institut National de la Santé et de la Recherche Médicale (FR) 2025-07-09 EP claimed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US claimed
US-20250090565-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YewSavin, Inc. (US) 2025-03-20 US claimed
CN-118235758-B Adipose-derived mesenchymal stem cell cryopreservation liquid and application thereof 吉林省微渺医疗科技有限公司 2025-02-28 CN claimed
CN-113995723-B Preparation method of sofalcel freeze-dried powder injection and product and application thereof 浙江普洛家园药业有限公司 2025-02-18 CN claimed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO claimed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP claimed
EP-0017808-B1 METHOD INVOLVING TESTING AN ELECTRICALLY ALTERABLE MICROELECTRONIC MEMORY CIRCUIT GENERAL INSTRUMENT CORPORATION (US) 1985-01-02 EP claimed
EP-0060190-B1 IMPROVEMENTS OF D.C. CONVERTERS P.S.A. Etudes & Recherches (FR) 1985-01-02 EP claimed
EP-0061212-B1 WHEELED VACUUM-CLEANER Koninklijke Philips Electronics N.V. (NL) 1984-09-12 EP claimed
EP-0117110-A2 Diesel engine fuel injection timing control system DEERE & COMPANY (US) 1984-08-29 EP claimed
US-4463733-A Closed loop fuel injection timing control DEERE & COMPANY (US) 1984-08-07 US claimed
EP-0077429-A1 Concrete girder for the efficient mounting of suspended ceilings and methods for installing ceilings Juillet, Christian (FR) 1983-04-27 EP claimed
EP-0003822-B1 DEVICE FOR DETERMINATION OF BLEEDING TIME AND BLEEDING CHARACTERISTICS OF A SMALL STANDARDIZED WOUND Hellige GmbH (DE) 1982-09-15 EP claimed
EP-0010721-B1 MONOAZO COMPOUNDS OF THE ACETOACETYLAMINOBENZENE SERIES, THEIR PREPARATION AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1981-11-25 EP claimed
EP-0000067-B1 DEVICE FOR THE ULTRASONIC INVESTIGATION AND REPRESENTATION OF AN OBJECT NEW YORK INSTITUTE OF TECHNOLOGY (US) 1981-02-25 EP claimed
EP-0012667-A1 Method of filtering an electric signal by charge transfer in a semi-conductor and switched capacitor filter utilizing such a method THOMSON-CSF (FR) 1980-06-25 EP claimed