SCHEMBL9364183

SCHEMBL9364183

CC(C)=CCOc1ccc(C(=O)/C=C/c2ccc(OCC(=O)O)cc2)c(OCC(=O)O)c1

nearest known ligand 0.98

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.98
MEN1 O00255 3/20 0.98
KMT2A Q03164 3/20 0.98
NR1I2 O75469 1/20 0.98
LMNA P02545 1/20 0.98
PGR P06401 1/20 0.98
ADRB2 P07550 1/20 0.98
ADRB1 P08588 1/20 0.98
ADORA3 P0DMS8 1/20 0.98
HPGD P15428 1/20 0.98
CNR1 P21554 1/20 0.98
TBXA2R P21731 1/20 0.98
SLC6A2 P23975 1/20 0.98
AGTR1 P30556 1/20 0.98
ADRA1A P35348 1/20 0.98
OPRD1 P41143 1/20 0.98
OPRK1 P41145 1/20 0.98
BLM P54132 1/20 0.98
SLC6A3 Q01959 1/20 0.98
ALOX5 P09917 4/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382974 1.00 MAPT (0.98) MAPTMEN1KMT2ANR1I2LMNA
SCHEMBL9364195 1.00 MAPT (0.98) MAPTMEN1KMT2ANR1I2LMNA
Sofalcone SCHEMBL40766 0.99 MAPT (1.00) MAPTMEN1KMT2ANR1I2LMNA
Sofalcone SCHEMBL24786 0.99 MAPT (1.00) MAPTMEN1KMT2ANR1I2LMNA
Sofalcone SCHEMBL30383975 0.99 MAPT (1.00) MAPTMEN1KMT2ANR1I2LMNA
Sofalcone SCHEMBL25214686 0.99 MAPT (1.00) MAPTMEN1KMT2ANR1I2LMNA
Sofalcone SCHEMBL29363342 0.99 MAPT (1.00) MAPTMEN1KMT2ANR1I2LMNA
Sofalcone SCHEMBL7842101 0.98 MAPT (0.98) MAPTMEN1KMT2ANR1I2LMNA
Sofalcone SCHEMBL10888696 0.95 MAPT (0.92) MAPTMEN1KMT2ANR1I2LMNA
SCHEMBL9368121 0.93 MAPT (0.89) MAPTMEN1KMT2ANR1I2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE33109-E ANTIULCER, ANTIINFLAMMATORY BIOREX LABORATORIES LIMITED (GB) 1989-11-07 US claimed
US-4656305-A ANTIINFLAMMATORY AND ANTIULCER AGENTS; ANTIALLERGENS; ANALGESICS BIOREX LABORATORIES, LIMITED (GB) 1987-04-07 US claimed
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
EP-0412803-B1 Chalcone derivatives TAISHO PHARMACEUTICAL CO LTD (JP) 1994-03-23 EP disclosed
US-5089654-A Antiulcer agents TAISHO PHARMACEUTICAL CO., LTD. (JP) 1992-02-18 US disclosed
EP-0412803-A1 Chalcone derivatives TAISHO PHARMACEUTICAL CO. LTD (JP) 1991-02-13 EP disclosed
US-RE33109-E ANTIULCER, ANTIINFLAMMATORY BIOREX LABORATORIES LIMITED (GB) 1989-11-07 US disclosed
US-4656305-A ANTIINFLAMMATORY AND ANTIULCER AGENTS; ANTIALLERGENS; ANALGESICS BIOREX LABORATORIES, LIMITED (GB) 1987-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885MEN1 3367/4885KMT2A 2792/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MEN1 2457/4885KMT2A 3188/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MEN1 2457/4885KMT2A 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.