Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP19 | O94966 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21229551 | 0.89 | USP19 (0.75) | USP19 | |
| SCHEMBL24787602 | 0.88 | USP19 (0.75) | USP19 | |
| SCHEMBL24787599 | 0.88 | USP19 (0.66) | USP19 | |
| SCHEMBL24787447 | 0.87 | USP19 (0.75) | USP19 | |
| SCHEMBL24786612 | 0.86 | USP19 (0.75) | USP19 | |
| SCHEMBL24787250 | 0.86 | USP19 (0.59) | USP19 | |
| SCHEMBL24787604 | 0.86 | USP19 (0.68) | USP19 | |
| SCHEMBL14735338 | 0.86 | USP7 (0.58) | USP19 | |
| SCHEMBL21229676 | 0.85 | USP19 (1.00) | USP19 | |
| SCHEMBL22032302 | 0.85 | USP19 (1.00) | USP19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746432-B1 | 4-HYDROXYPIPERIDINE DERIVATIVES AND THEIR USE AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | ALMAC DISCOVERY LTD (GB) | 2022-12-14 | — | — | EP | disclosed |