SCHEMBL24788935

SCHEMBL24788935

c1ccc(-c2nc(-c3cccc(-c4cccnc4)c3)cc(-c3ccc(-c4ccc5c6ccccc6n(-c6ccccc6)c5c4)c4ccccc34)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 1/20 0.37
▸ MAPT P10636 2/20 0.36
▸ KMO O15229 1/20 0.36
▸ MAPK14 Q16539 1/20 0.36
▸ CYP19A1 P11511 2/20 0.36
▸ CYP11B1 P15538 2/20 0.36
▸ CYP17A1 P05093 1/20 0.36
▸ CYP11B2 P19099 1/20 0.36
▸ GRM5 P41594 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ ATM Q13315 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ METAP2 P50579 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ TSHR P16473 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ GLA P06280 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24752202 0.97 DHODH (0.39) DHODHMAPTKMOMAPK14CYP19A1
SCHEMBL24752480 0.94 DHODH (0.37) DHODHMAPTKMOMAPK14CYP19A1
SCHEMBL26432151 0.94 DHODH (0.43) DHODHMAPTMAPK14CYP19A1CYP11B1
SCHEMBL24752199 0.93 DHODH (0.42) DHODHMAPTCYP19A1CYP11B1CYP17A1
SCHEMBL24787757 0.93 DHODH (0.39) DHODHMAPTKMOMAPK14CYP19A1
SCHEMBL26432100 0.93 MAPT (0.40) DHODHMAPTKMOMAPK14CYP19A1
SCHEMBL22113764 0.92 DHODH (0.44) DHODHMAPTKMOCYP19A1CYP11B1
SCHEMBL19397486 0.92 DHODH (0.44) DHODHMAPTKMOCYP19A1CYP11B1
SCHEMBL24788932 0.91 DHODH (0.39) DHODHMAPTKMOMAPK14CYP19A1
SCHEMBL24753859 0.91 KDM4E (0.41) MAPTKDM4EATML3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230127629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-04-27 — — US disclosed
US-20230127629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-04-27 — — US disclosed
EP-4101847-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE Idemitsu Kosan Co., Ltd (JP) 2022-12-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE L1CAM, EPCAM, TMEM109 DHODH 3470/4885MAPT 1120/4885KMO 4084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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