Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.35 |
| ▸ | GCK | P35557 | 4/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18612320 | 0.90 | IAPP (0.37) | IAPPFFAR4CYP4F2CYP4A11MTNR1A | |
| SCHEMBL20324945 | 0.89 | IAPP (0.36) | IAPPFFAR4CYP4F2CYP4A11MTNR1A | |
| SCHEMBL21472028 | 0.89 | CYP4F2 (0.38) | FFAR4CYP4F2CYP4A11MTNR1AMTNR1B | |
| SCHEMBL20443306 | 0.89 | CYP4F2 (0.38) | FFAR4CYP4F2CYP4A11MTNR1AMTNR1B | |
| SCHEMBL20326096 | 0.89 | IAPP (0.36) | IAPPFFAR4CYP4F2CYP4A11MTNR1A | |
| SCHEMBL23350109 | 0.88 | IAPP (0.34) | IAPPFFAR4CYP4F2CYP4A11MTNR1A | |
| SCHEMBL20443669 | 0.87 | IAPP (0.35) | IAPPFFAR4CYP4F2CYP4A11MTNR1A | |
| SCHEMBL20046556 | 0.87 | IAPP (0.35) | IAPPFFAR4CYP4F2CYP4A11MTNR1A | |
| SCHEMBL21907822 | 0.81 | CYP4F2 (0.33) | FFAR4CYP4F2CYP4A11MTNR1AMTNR1B | |
| SCHEMBL24856386 | 0.79 | MTNR1B (0.37) | IAPPMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402907-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | YALE UNIVERSITY | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402907-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | MDM2, CRBN, VHL | IAPP 1028/4885FFAR4 4732/4885CYP4F2 4388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.