Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 8/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL814567 | 1.00 | SLC9A1 (0.48) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL7655989 | 0.86 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL248385 | 0.86 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL18272394 | 0.86 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL248384 | 0.86 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL18272446 | 0.86 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL15196464 | 0.86 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL12915852 | 0.86 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL29488083 | 0.86 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL22654465 | 0.85 | KDM1A (0.58) | SLC9A1KDM1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013124280-A1 | SYNTHESIS OF 2-(3,4-DIFLUOROPHENYL)CYCLOPROPANECARBOXYLIC ACID | LEK PHARMACEUTICALS D.D. (SI) | 2013-08-29 | — | — | WO | disclosed |
| EP-2588441-A2 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | Actavis Group Ptc Ehf (IS) | 2013-05-08 | — | — | EP | disclosed |
| EP-2560939-A2 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES | Actavis Group Ptc Ehf (IS) | 2013-02-27 | — | — | EP | disclosed |
| WO-2012001531-A2 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | ACTAVIS GROUP PTC EHF (IS) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011132083-A2 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES | ACTAVIS GROUP PTC EHF (IS) | 2011-10-27 | — | — | WO | disclosed |