Methacrylic Acid

Methacrylic Acid

SCHEMBL2479561

C=C(C)C(=O)O.CN1C(=O)C=CC1=O

nearest known ligand 0.59

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.59
GSK3A P49840 2/20 0.59
GSK3B P49841 2/20 0.59
PTGS1 P23219 5/20 0.34
PTGS2 P35354 5/20 0.34
DDAH1 O94760 1/20 0.32
NSD2 O96028 1/20 0.32
G6PD P11413 1/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
ALDH1A1 P00352 4/20 0.31
BLM P54132 2/20 0.31
HPGD P15428 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
WRN Q14191 1/20 0.31
HIF1A Q16665 1/20 0.31
LMNA P02545 2/20 0.31
MAPT P10636 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL976025 0.85 MGLL (0.72) MGLLGSK3AGSK3BPTGS1PTGS2
SCHEMBL25436194 0.77 MGLL (1.00) MGLLGSK3AGSK3BPTGS1PTGS2
SCHEMBL36966 0.77
Benzoquinone SCHEMBL8160581 0.75 MIF (0.46) ALDH1A1BLMHPGDMAPTTDP1
Benzoquinone SCHEMBL1437638 0.75 MIF (0.46) ALDH1A1BLMHPGDMAPTTDP1
Benzoquinone SCHEMBL10955839 0.75 MIF (0.46) ALDH1A1BLMHPGDMAPTTDP1
Methacrylic Acid SCHEMBL3421717 0.71 TDP1 (0.47) ALDH1A1HPGDLMNAMAPTNPSR1
Methacrylic Acid SCHEMBL225835 0.71 TDP1 (0.47) ALDH1A1HPGDLMNAMAPTNPSR1
Methacrylic Acid SCHEMBL3426195 0.71 TDP1 (0.47) ALDH1A1HPGDLMNAMAPTNPSR1
Methacrylic Acid SCHEMBL3858692 0.71 TDP1 (0.47) ALDH1A1HPGDLMNAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2214902-B1 HIGH CONTRAST DECORATIVE SHEETS AND LAMINATES DU PONT (US) 2011-10-19 EP disclosed
US-20080268214-A1 Decorative safety glass E. I. DU PONT DE NEMOURS AND COMPANY 2008-10-30 US disclosed
US-20080233377-A1 High contrast high strength decorative sheets and laminates E. I. DU PONT DE NEMOURS AND COMPANY 2008-09-25 US disclosed
US-20070196630-A1 Decorative solar control laminates E. I. DU PONT DE NEMOURS AND COMPANY 2007-08-23 US disclosed