SCHEMBL2479562

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2476348	0.88	JAK3 (0.52)	RPS6KB1AURKAJAK3JAK2IRAK4
	SCHEMBL2482471	0.88	RPS6KB1 (0.60)	RPS6KB1AURKAJAK3JAK2IRAK4
	SCHEMBL12456033	0.86	RPS6KB1 (0.54)	RPS6KB1AURKAJAK3JAK2IRAK4
	SCHEMBL2479053	0.86	KDM4E (0.51)	JAK3JAK2IRAK4JAK1TYK2
	SCHEMBL2480282	0.86	JAK3 (0.67)	RPS6KB1JAK3JAK2IRAK4JAK1
	SCHEMBL2484302	0.86	JAK3 (0.49)	RPS6KB1AURKAJAK3JAK2IRAK4
	SCHEMBL12206941	0.86	JAK3 (0.55)	RPS6KB1AURKAJAK3JAK2IRAK4
	SCHEMBL2475770	0.85	CDC7 (0.58)	RPS6KB1AURKAJAK3JAK2IRAK4
	SCHEMBL12330858	0.85	JAK3 (0.51)	RPS6KB1AURKAJAK3JAK2IRAK4
	SCHEMBL2694894	0.85	JAK3 (0.51)	RPS6KB1AURKAJAK3JAK2IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.