Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | SCD | O00767 | 11/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12199473 | 0.93 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTTP53SCDNPC1 | |
| Trifluoromethanesulfonic Acid SCHEMBL2485817 | 0.92 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTTP53SCDNPC1 | |
| Trifluoroacetic Acid SCHEMBL2483587 | 0.87 | SCD (0.70) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2483973 | 0.87 | MAPT (0.59) | SMN1; SMN2MAPTTP53SCDNPC1 | |
| Trifluoroacetic Acid SCHEMBL2482555 | 0.83 | MAP3K5 (0.61) | SMN1; SMN2MAPTTP53SCDNPC1 | |
| SCHEMBL12199452 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTTP53SCDNPC1 | |
| Bromide SCHEMBL2483413 | 0.81 | SMN1; SMN2 (0.69) | SMN1; SMN2MAPTTP53SCDNPC1 | |
| SCHEMBL2484653 | 0.80 | SCD (0.81) | SCDNPC1RAB9AKMT2AMEN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL403207 | 0.79 | SCD (0.67) | MAPTSCDNPC1RAB9AKMT2A | |
| SCHEMBL3347093 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPTTP53SCDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376463-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | Bayer Pharma Aktiengesellschaft (DE) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |