Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 18/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484653 | 0.92 | SCD (0.81) | SCDKMT2ANPC1RAB9AMEN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL403207 | 0.91 | SCD (0.67) | SCDKMT2ANPC1RAB9AMEN1 | |
| Trifluoroacetic Acid SCHEMBL2482555 | 0.88 | MAP3K5 (0.61) | SCDKMT2ANPC1RAB9AMEN1 | |
| Trifluoroacetic Acid SCHEMBL2479571 | 0.87 | SMN1; SMN2 (0.61) | SCDKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL2482852 | 0.85 | SCD (0.66) | SCDKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL4912951 | 0.83 | SCD (1.00) | SCDKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL16554160 | 0.81 | SCD (1.00) | SCDKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL4917823 | 0.81 | SCD (0.87) | SCDKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL31243 | 0.81 | SCD (1.00) | SCDKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL16554145 | 0.80 | SCD (0.88) | SCDKMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376463-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | Bayer Pharma Aktiengesellschaft (DE) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |