Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2479589 | 1.00 | CYP1A2 (0.58) | CYP1A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10793988 | 0.92 | CYP1A2 (0.54) | CYP1A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6953181 | 0.89 | CYP1A2 (0.56) | CYP1A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6953177 | 0.89 | CYP1A2 (0.56) | CYP1A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6953185 | 0.89 | CYP1A2 (0.70) | CYP1A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL269514 | 0.83 | MAPT (0.53) | CYP1A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2630510 | 0.83 | MAPT (0.53) | CYP1A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8437177 | 0.83 | ALDH1A1 (0.47) | CYP1A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8437175 | 0.83 | ALDH1A1 (0.47) | CYP1A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11433045 | 0.83 | CYP1A2 (0.61) | CYP1A2MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108273478-B | Formaldehyde removal composition and product | 李怀玉 | 2021-03-02 | — | — | CN | disclosed |
| CN-108273478-A | A kind of formaldehyde removing composition and product | 李怀玉 | 2018-07-13 | — | — | CN | disclosed |
| US-8883935-B2 | High refractive index composition | BATTELLE MEMORIAL INSTITUTE (US) | 2014-11-11 | — | — | US | disclosed |
| EP-2563826-A2 | HIGH REFRACTIVE INDEX COMPOSITION | Battelle Memorial Institute (US) | 2013-03-06 | — | — | EP | disclosed |
| US-20130046054-A1 | HIGH REFRACTIVE INDEX COMPOSITION | BATTELLE MEMORIAL INSTITUTE (US) | 2013-02-21 | — | — | US | disclosed |
| EP-2373641-B1 | PYRIDAZINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-12-19 | — | — | EP | disclosed |
| US-8178538-B2 | Pyridazinones | HOFFMANN-LA ROCHE INC. (US) | 2012-05-15 | — | — | US | disclosed |
| WO-2011139856-A2 | HIGH REFRACTIVE INDEX COMPOSITION | BATTELLE MEMORIAL INSTITUTE (US) | 2011-11-10 | — | — | WO | disclosed |
| EP-2373641-A1 | PYRIDAZINONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2011-10-12 | — | — | EP | disclosed |
| US-20100152193-A1 | PYRIDAZINONES | HOFFMANN-LA ROCHE, INC. | 2010-06-17 | — | — | US | disclosed |
| WO-2010063610-A1 | PYRIDAZINONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-06-10 | — | — | WO | disclosed |
| EP-0727421-A1 | Agents for improving sleep | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-08-21 | — | — | EP | disclosed |
| US-5026853-A | Sleep and cardiovascular disorders | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-06-25 | — | — | US | disclosed |
| US-4968684-A | N-ARYL-PIPERAZINEALKANAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-11-06 | — | — | US | disclosed |
| US-4880808-A | SEDATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152193-A1 | PYRIDAZINONES | PDE5A, PDE3A, PDE10A | CYP1A2 87/4885MAPT 2313/4885NPC1 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.