SCHEMBL24796037

SCHEMBL24796037

C[C@]12C=C[C@H](C1)C(=O)N2CCNC(=O)CSCC(=O)O

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.33
▸ FABP3 P05413 1/20 0.33
▸ FABP4 P15090 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ ALDH1A1 P00352 2/20 0.31
▸ USP2 O75604 1/20 0.31
▸ MITF O75030 1/20 0.31
▸ KLF5 Q13887 1/20 0.31
▸ CYP3A4 P08684 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30
▸ TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24796421 0.74 USP2 (0.34) GAAFABP3FABP4L3MBTL1ALDH1A1
SCHEMBL24796381 0.74 GAA (0.35) GAAFABP3FABP4L3MBTL1SMN1; SMN2
SCHEMBL24796186 0.72 GAA (0.36) GAAFABP3FABP4L3MBTL1SMN1; SMN2
SCHEMBL21389177 0.71 GAA (0.36) GAAFABP3FABP4L3MBTL1SMN1; SMN2
SCHEMBL24796132 0.69 GAA (0.38) GAAFABP3FABP4L3MBTL1SMN1; SMN2
SCHEMBL21383928 0.69 GAA (0.38) GAAFABP3FABP4L3MBTL1SMN1; SMN2
SCHEMBL24796127 0.69 GAA (0.38) GAAFABP3FABP4L3MBTL1SMN1; SMN2
SCHEMBL24796115 0.69 GAA (0.38) GAAFABP3FABP4L3MBTL1SMN1; SMN2
SCHEMBL24795885 0.69 USP2 (0.39) GAAFABP3FABP4L3MBTL1SMN1; SMN2
SCHEMBL21389158 0.69 USP2 (0.39) GAAFABP3FABP4L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR GAA 1536/4885FABP3 669/4885FABP4 1018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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