SCHEMBL24796186

SCHEMBL24796186

O=C(O)CSCC(=O)NCCN1C(=O)[C@@H]2C=C[C@H]1C2

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.36
▸ FABP4 P15090 3/20 0.35
▸ FABP3 P05413 2/20 0.35
▸ L3MBTL1 Q9Y468 3/20 0.34
▸ ALDH1A1 P00352 5/20 0.33
▸ LMNA P02545 1/20 0.33
▸ MITF O75030 1/20 0.33
▸ KLF5 Q13887 1/20 0.33
▸ TSHR P16473 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ USP2 O75604 1/20 0.31
▸ SMN1; SMN2 Q16637 2/20 0.31
▸ CYP3A4 P08684 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26747718 0.89 KMT2A (0.36) ALDH1A1
SCHEMBL24796676 0.85 HPGD (0.43) GAAL3MBTL1ALDH1A1LMNAMITF
SCHEMBL24796422 0.74 MITF (0.36) GAAFABP4FABP3L3MBTL1ALDH1A1
SCHEMBL21389244 0.74 MITF (0.36) GAAFABP4FABP3L3MBTL1ALDH1A1
SCHEMBL26744109 0.74 GAA (0.38) GAAFABP4FABP3L3MBTL1ALDH1A1
SCHEMBL26752482 0.74 GAA (0.38) GAAFABP4FABP3L3MBTL1ALDH1A1
SCHEMBL24796037 0.72 GAA (0.33) GAAFABP4FABP3L3MBTL1ALDH1A1
SCHEMBL21389158 0.72 USP2 (0.39) GAAFABP4FABP3L3MBTL1ALDH1A1
SCHEMBL24795885 0.72 USP2 (0.39) GAAFABP4FABP3L3MBTL1ALDH1A1
SCHEMBL21389394 0.71 GAA (0.38) GAAFABP4FABP3L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR GAA 1526/4885FABP4 1047/4885FABP3 666/4885
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR GAA 1536/4885FABP4 1018/4885FABP3 669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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