SCHEMBL24796116

SCHEMBL24796116

O=C(O)CSCC(=O)NCCN1C(=O)CC2(CCCC2)C1=O

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ FABP3 P05413 1/20 0.37
▸ FABP4 P15090 1/20 0.37
▸ GAA P10253 1/20 0.36
▸ CHRM2 P08172 1/20 0.35
▸ CHRM3 P20309 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ ADRA1A P35348 1/20 0.34
▸ ADRA1B P35368 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.33
▸ KMT2A Q03164 1/20 0.31
▸ USP2 O75604 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24796304 0.90 CHRM2 (0.35) CHRM2CHRM3ADRA1AADRA1BALDH1A1
SCHEMBL24796305 0.85 HPGD (0.40) GAAL3MBTL1ALDH1A1KMT2A
SCHEMBL21389277 0.84 GAA (0.38) FABP3FABP4GAAL3MBTL1ALDH1A1
SCHEMBL21389194 0.80 GAA (0.36) FABP3FABP4GAAL3MBTL1ALDH1A1
SCHEMBL21389123 0.79 GAA (0.36) FABP3FABP4GAAL3MBTL1ALDH1A1
SCHEMBL21389253 0.79 GAA (0.34) FABP3FABP4GAAL3MBTL1ALDH1A1
SCHEMBL21389091 0.78 KMT2A (0.40) FABP3FABP4GAAL3MBTL1ALDH1A1
SCHEMBL21389103 0.77 KMT2A (0.44) FABP3FABP4GAAL3MBTL1ALDH1A1
SCHEMBL24796113 0.76 TSHR (0.51) FABP3FABP4GAAL3MBTL1ALDH1A1
SCHEMBL21389154 0.73 GAA (0.40) FABP3FABP4GAAL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR FABP3 666/4885FABP4 1047/4885GAA 1526/4885
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR FABP3 669/4885FABP4 1018/4885GAA 1536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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