SCHEMBL24796113

SCHEMBL24796113

O=C(O)CSCC(=O)NCCN1C(=O)CNC1=O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.51
▸ GAA P10253 1/20 0.37
▸ FABP3 P05413 1/20 0.36
▸ FABP4 P15090 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ PDE7A Q13946 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ GSK3A P49840 1/20 0.35
▸ GSK3B P49841 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.34
▸ KMT2A Q03164 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24796000 0.84 L3MBTL1 (0.41) TSHRL3MBTL1PDE7ALMNAALDH1A1
SCHEMBL21389103 0.82 KMT2A (0.44) GAAFABP3FABP4L3MBTL1LMNA
SCHEMBL21389356 0.82 HPGD (0.43) TSHRGAAL3MBTL1PDE7ALMNA
SCHEMBL21383907 0.80 TSHR (0.35) TSHRGAAFABP3FABP4L3MBTL1
SCHEMBL21389091 0.80 KMT2A (0.40) TSHRGAAFABP3FABP4L3MBTL1
SCHEMBL24796263 0.77 USP2 (0.39) GAAFABP3FABP4L3MBTL1LMNA
SCHEMBL24796268 0.77 ALDH1A1 (0.40) GAAFABP3FABP4L3MBTL1PDE7A
SCHEMBL21383876 0.77 ALDH1A1 (0.39) GAAFABP3FABP4L3MBTL1ALDH1A1
SCHEMBL21389194 0.77 GAA (0.36) GAAFABP3FABP4L3MBTL1LMNA
SCHEMBL21389211 0.77 GAA (0.55) TSHRGAAL3MBTL1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR TSHR 140/4885GAA 1526/4885FABP3 666/4885
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR TSHR 142/4885GAA 1536/4885FABP3 669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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