SCHEMBL247963

SCHEMBL247963

C=CC=CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
ALDH1A1 P00352 1/20 0.52
FAAH O00519 2/20 0.50
TRPV1 Q8NER1 1/20 0.50
FASN P49327 1/20 0.50
MEN1 O00255 1/20 0.44
CYP3A4 P08684 1/20 0.44
KMT2A Q03164 1/20 0.44
TERT O14746 2/20 0.43
GMNN O75496 1/20 0.43
USP2 O75604 1/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43
ALOX15 P16050 1/20 0.43
APEX1 P27695 1/20 0.43
CYP2C19 P33261 1/20 0.43
RECQL P46063 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217012 1.00 TSHR (0.56) TSHRALDH1A1FAAHTRPV1FASN
SCHEMBL215949 1.00 TSHR (0.56) TSHRALDH1A1FAAHTRPV1FASN
SCHEMBL20914398 1.00 TSHR (0.56) TSHRALDH1A1FAAHTRPV1FASN
SCHEMBL501697 1.00 TSHR (0.56) TSHRALDH1A1FAAHTRPV1FASN
SCHEMBL22468755 1.00 TSHR (0.56) TSHRALDH1A1FAAHTRPV1FASN
SCHEMBL215938 1.00 TSHR (0.56) TSHRALDH1A1FAAHTRPV1FASN
SCHEMBL217258 1.00 TSHR (0.56) TSHRALDH1A1FAAHTRPV1FASN
SCHEMBL22468753 1.00 TSHR (0.56) TSHRALDH1A1FAAHTRPV1FASN
SCHEMBL20914400 1.00 TSHR (0.56) TSHRALDH1A1FAAHTRPV1FASN
SCHEMBL151177 1.00 TSHR (0.56) TSHRALDH1A1FAAHTRPV1FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11318072-B2 Matt-effect composition comprising hydrophobic aerogel particles and silicone elastomer particles L'OREAL (FR) 2022-05-03 US disclosed
US-20200069537-A1 MATT-EFFECT COMPOSITION COMPRISING HYDROPHOBIC AEROGEL PARTICLES AND SILICONE ELASTOMER PARTICLES L'OREAL (FR) 2020-03-05 US disclosed
EP-2345456-B1 ANHYDROUS LIQUID SCREENING COMPOSITION CONTAINING AN OILY PHASE, A SPECIFIC TRIAZINE FILTER AND AN OILY REOLOGICAL THICKENING OR GELIFYING AGENT. L'ORÉAL (FR) 2017-05-03 EP disclosed
US-20150320648-A1 MATT-EFFECT COMPOSITION COMPRISING HYDROPHOBIC AEROGEL PARTICLES AND SILICONE ELASTOMER PARTICLES L'OREAL (FR) 2015-11-12 US disclosed
US-9050270-B2 Cosmetic method using a composition containing siloxane resins and fillers L'OREAL (FR) 2015-06-09 US disclosed
US-9017705-B2 Cosmetic method using a composition containing siloxane resins and a non-volatile oil L'OREAL (FR) 2015-04-28 US disclosed
EP-2358345-B1 COSMETIC METHOD USING A COMPOSITION CONTAINING SILOXANE RESINS AND A POWDER DYE ORÉAL L (FR) 2015-04-08 EP disclosed
US-8747828-B2 Cosmetic method using a composition containing siloxane resins and specific non-ionic surfactant L'OREAL (FR) 2014-06-10 US disclosed
EP-2358347-B1 COSMETIC METHOD USING A COMPOSITION CONTAINING SILOXANE RESINS AND A NON-IONIC SILICONE SURFACTANT OREAL (FR) 2014-02-26 EP disclosed
WO-2013190138-A1 MATT-EFFECT COMPOSITION COMPRISING HYDROPHOBIC AEROGEL PARTICLES AND SILICONE ELASTOMER PARTICLES L'OREAL (FR) 2013-12-27 WO disclosed
WO-2010063959-A2 COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD L'OREAL (FR) 2010-06-10 WO disclosed
WO-2010063963-A2 COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD L'OREAL (FR) 2010-06-10 WO disclosed
WO-2010063961-A2 COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD L'OREAL (FR) 2010-06-10 WO disclosed
WO-2010063964-A2 COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD L'OREAL (FR) 2010-06-10 WO disclosed
WO-2010063954-A2 COSMETIC METHOD USING A COMPOSITION CONTAINING SILOXANE RESINS AND A POWDER DYE L'OREAL (FR) 2010-06-10 WO disclosed
WO-2010063955-A2 COSMETIC METHOD USING A COMPOSITION CONTAINING SILOXANE RESINS AND A NON-VOLATILE OIL L'OREAL (FR) 2010-06-10 WO disclosed
WO-2010063968-A2 COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIAL AND MAKE-UP METHOD L'OREAL (FR) 2010-06-10 WO disclosed
US-20040234477-A1 Composition and cosmetic preparation containing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-11-25 US disclosed
EP-1426027-A9 COMPOSITION AND COSMETIC PREPARATION CONTAINING THE SAME Shin-Etsu Chemical Company, Ltd. (JP) 2004-10-27 EP disclosed
EP-1426027-A1 COMPOSITION AND COSMETIC PREPARATION CONTAINING THE SAME Shin-Etsu Chemical Company, Ltd. (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150320648-A1 MATT-EFFECT COMPOSITION COMPRISING HYDROPHOBIC AEROGEL PARTICLES AND SILICONE ELASTOMER PARTICLES CUTA, MATR3, FAM83E TSHR 3281/4885ALDH1A1 3378/4885FAAH 664/4885
US-20200069537-A1 MATT-EFFECT COMPOSITION COMPRISING HYDROPHOBIC AEROGEL PARTICLES AND SILICONE ELASTOMER PARTICLES CUTA, MATR3, FAM83E TSHR 3281/4885ALDH1A1 3378/4885FAAH 664/4885
US-11318072-B2 Matt-effect composition comprising hydrophobic aerogel particles and silicone elastomer particles CUTA, MATR3, FAM83E TSHR 3281/4885ALDH1A1 3378/4885FAAH 664/4885
US-20040234477-A1 Composition and cosmetic preparation containing the same COLGALT1, CUTA, SS18L2 TSHR 535/4885ALDH1A1 2449/4885FAAH 1021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.