SCHEMBL24796657

SCHEMBL24796657

C[C@H]1CCC(=O)N(CCNC(=O)CSCC(=O)NC2CC2)C1=O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ ALDH1A1 P00352 3/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ KMT2A Q03164 4/20 0.36
▸ HPGD P15428 3/20 0.36
▸ LMNA P02545 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ MEN1 O00255 2/20 0.34
▸ TSHR P16473 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ HTT P42858 1/20 0.33
▸ CHRM1 P11229 1/20 0.33
▸ MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24796005 1.00 L3MBTL1 (0.39) L3MBTL1ALDH1A1RAB9AKMT2AHPGD
SCHEMBL24796656 0.95 HPGD (0.39) L3MBTL1ALDH1A1RAB9AKMT2AHPGD
SCHEMBL21389152 0.95 HPGD (0.41) L3MBTL1ALDH1A1RAB9AKMT2AHPGD
SCHEMBL21389295 0.95 HPGD (0.41) L3MBTL1ALDH1A1RAB9AKMT2AHPGD
SCHEMBL24796659 0.89 L3MBTL1 (0.40) L3MBTL1ALDH1A1RAB9AKMT2AHPGD
SCHEMBL24796403 0.89 L3MBTL1 (0.40) L3MBTL1ALDH1A1RAB9AKMT2AHPGD
SCHEMBL24796616 0.88 USP2 (0.39) L3MBTL1ALDH1A1KMT2AHPGDSMN1; SMN2
SCHEMBL24796003 0.84 CYP1A2 (0.37) L3MBTL1ALDH1A1RAB9AKMT2ASMN1; SMN2
SCHEMBL24796401 0.82 HPGD (0.41) L3MBTL1ALDH1A1RAB9AKMT2AHPGD
SCHEMBL21389270 0.82 HPGD (0.44) L3MBTL1ALDH1A1RAB9AKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR L3MBTL1 2127/4885ALDH1A1 3305/4885RAB9A 664/4885
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR L3MBTL1 2161/4885ALDH1A1 3367/4885RAB9A 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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