Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | SDHA | P31040 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CALML3 | P27482 | 1/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701777 | 0.91 | MAOA (0.51) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL2109046 | 0.89 | MAOA (0.49) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5982107 | 0.85 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL702819 | 0.83 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL2108790 | 0.81 | MAOA (0.55) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL541127 | 0.81 | CALML3 (0.47) | MAOAMAOBCALML3 | |
| SCHEMBL541126 | 0.81 | CALML3 (0.47) | MAOAMAOBCALML3 | |
| SCHEMBL2109814 | 0.80 | MAOA (0.46) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL2108909 | 0.80 | MAOA (0.53) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL2108908 | 0.80 | MAOA (0.55) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374806-B1 | OXAZOLIDINON-QUINOLONE HYBRIDES AND INTERMEDIATES FOR THEIR PREPARATION | MORPHOCHEM AG FÜR KOMBINATORISCHE CHEMIE (DE) | 2016-11-02 | — | — | EP | disclosed |
| EP-1660489-B1 | INTERMEDIATE PRODUCTS FOR PRODUCING OXAZOLIDINONE-QUINOLONE HYBRIDS | MORPHOCHEM AG FÜR KOMBINATORISCHE CHEMIE (DE) | 2014-07-02 | — | — | EP | disclosed |
| EP-2374806-A1 | OXAZOLIDINON-QUINOLONe HYBRIDes and intermediates for their preparation | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2011-10-12 | — | — | EP | disclosed |
| EP-1660489-A1 | INTERMEDIATE PRODUCTS FOR PRODUCING OXAZOLIDINONE-QUINOLONE HYBRIDS | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005023801-A1 | INTERMEDIATE PRODUCTS FOR PRODUCING OXAZOLIDINONE-QUINOLONE HYBRIDS | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2005-03-17 | — | — | WO | disclosed |