Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.45 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | STAT6 | P42226 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18943720 | 0.77 | SIGMAR1 (0.41) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31254406 | 0.73 | SIGMAR1 (0.42) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2915914 | 0.73 | GRIN2D (0.42) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1238995 | 0.69 | SIGMAR1 (0.57) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4972287 | 0.69 | SIGMAR1 (0.38) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4394773 | 0.69 | SIGMAR1 (0.41) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15827308 | 0.69 | GRIN2D (0.38) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL12439809 | 0.69 | SIGMAR1 (0.38) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL985709 | 0.67 | ABL1 (0.39) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL985712 | 0.67 | ABL1 (0.39) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011140009-A1 | METHODS OF USING SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | BIOMARIN PHARMACEUTICAL INC. (US) | 2011-11-10 | — | — | WO | claimed |
| EP-2373694-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | BioMarin Pharmaceutical Inc. (US) | 2011-10-12 | — | — | EP | claimed |
| EP-2238102-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | Lead Therapeutics, Inc. (US) | 2010-10-13 | — | — | EP | claimed |
| WO-2010065174-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-06-10 | — | — | WO | claimed |
| WO-2010048340-A2 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-04-29 | — | — | WO | claimed |
| WO-2009085562-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2009-07-09 | — | — | WO | claimed |
| WO-2008140973-A1 | SEMI-SYNTHETIC GLYCOPEPTIDES WITH ANTIBACTERIAL ACTIVITY | LEAD THERAPEUTICS, INC. (US) | 2008-11-20 | — | — | WO | claimed |
| EP-1868630-A2 | SEMI-SYNTHETIC DESMETHYL-VANCOMYCIN-BASED GLYCOPEPTIDES WITH ANTIBIOTIC ACTIVITY | Novartis Vaccines and Diagnostics, Inc. (US) | 2007-12-26 | — | — | EP | claimed |
| EP-1858908-A2 | SEMI-SYNTHETIC REARRANGED VANCOMYCIN/DESMETHYL-VANCOMYCIN-BASED GLYCOPEPTIDES WITH ANTIBIOTIC ACTIVITY | Novartis Vaccines and Diagnostics, Inc. (US) | 2007-11-28 | — | — | EP | claimed |
| WO-2006093933-A2 | SEMI-SYNTHETIC REARRANGED VANCOMYCIN/DESMETHYL-VANCOMYCIN-BASED GLYCOPEPTIDES WITH ANTIBIOTIC ACTIVITY | NOVARTIS VACCINES AND DIAGNOSTICS INC. (US) | 2006-09-08 | — | — | WO | claimed |
| WO-2006094082-A2 | SEMI-SYNTHETIC DESMETHYL-VANCOMYCIN-BASED GLYCOPEPTIDES WITH ANTIBIOTIC ACTIVITY | NOVARTIS VACCINES AND DIAGNOSTICS INC. (US) | 2006-09-08 | — | — | WO | claimed |
| WO-2011140009-A1 | METHODS OF USING SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | BIOMARIN PHARMACEUTICAL INC. (US) | 2011-11-10 | — | — | WO | disclosed |
| EP-2373694-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | BioMarin Pharmaceutical Inc. (US) | 2011-10-12 | — | — | EP | disclosed |
| EP-2238102-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | Lead Therapeutics, Inc. (US) | 2010-10-13 | — | — | EP | disclosed |
| WO-2010065174-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |
| EP-1861115-A2 | SEMI-SYNTHETIC GLYCOPEPTIDES WITH ANTIBIOTIC ACTIVITY | Novartis Vaccines and Diagnostics, Inc. (US) | 2007-12-05 | — | — | EP | disclosed |
| EP-1858908-A2 | SEMI-SYNTHETIC REARRANGED VANCOMYCIN/DESMETHYL-VANCOMYCIN-BASED GLYCOPEPTIDES WITH ANTIBIOTIC ACTIVITY | Novartis Vaccines and Diagnostics, Inc. (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006093947-A2 | SEMI-SYNTHETIC GLYCOPEPTIDES WITH ANTIBIOTIC ACTIVITY | NOVARTIS VACCINES AND DIAGNOSTICS INC. (US) | 2006-09-08 | — | — | WO | disclosed |
| WO-2006093933-A2 | SEMI-SYNTHETIC REARRANGED VANCOMYCIN/DESMETHYL-VANCOMYCIN-BASED GLYCOPEPTIDES WITH ANTIBIOTIC ACTIVITY | NOVARTIS VACCINES AND DIAGNOSTICS INC. (US) | 2006-09-08 | — | — | WO | disclosed |
| WO-2006094082-A2 | SEMI-SYNTHETIC DESMETHYL-VANCOMYCIN-BASED GLYCOPEPTIDES WITH ANTIBIOTIC ACTIVITY | NOVARTIS VACCINES AND DIAGNOSTICS INC. (US) | 2006-09-08 | — | — | WO | disclosed |