SCHEMBL24798951

SCHEMBL24798951

N#CC(C#N)=C1C=CC(=C(C#N)C#N)CC1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.34
ALDH1A1 P00352 5/20 0.33
MEN1 O00255 5/20 0.33
USP2 O75604 5/20 0.33
HTT P42858 5/20 0.33
KMT2A Q03164 5/20 0.33
LMNA P02545 4/20 0.33
MAPT P10636 4/20 0.33
POLB P06746 2/20 0.33
RECQL P46063 2/20 0.33
GPR55 Q9Y2T6 1/20 0.33
MAPK1 P28482 1/20 0.33
BLM P54132 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.32
GAA P10253 1/20 0.31
GPR35 Q9HC97 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14612944 0.82 EGFR (0.30) EGFR
SCHEMBL29141813 0.76 ALDH1A1 (0.38) EGFRALDH1A1MEN1USP2HTT
SCHEMBL14612943 0.72 GSK3A (0.43) EGFR
SCHEMBL28253704 0.67
SCHEMBL9116321 0.67
SCHEMBL9144596 0.67
SCHEMBL24134603 0.67
SCHEMBL14613101 0.66 MEN1 (0.41) EGFRALDH1A1MEN1USP2HTT
SCHEMBL2786474 0.65 ALDH1A1 (0.46) EGFRALDH1A1HSD17B10
SCHEMBL10933892 0.64 MEN1 (0.33) ALDH1A1MEN1USP2HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4109544-A1 DISPLAY APPARATUS Samsung Display Co., Ltd. (KR) 2022-12-28 EP disclosed