Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | MLNR | O43193 | 6/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377226 | 0.90 | ITGB3 (0.37) | NAMPTMLNRRORCCYP2D6CA12 | |
| SCHEMBL19377472 | 0.90 | IDH1 (0.46) | IDH1 | |
| SCHEMBL19377245 | 0.86 | MLNR (0.42) | NAMPTMLNRRORCCYP2C9CYP2D6 | |
| SCHEMBL19377448 | 0.86 | MLNR (0.40) | NAMPTMLNRRORCCYP2C9DRD2 | |
| SCHEMBL19377218 | 0.86 | HSD17B10 (0.49) | NAMPTMLNRRORCCYP2C9CA12 | |
| SCHEMBL19377663 | 0.86 | HSD17B10 (0.49) | NAMPTMLNRRORCCYP2C9CA12 | |
| SCHEMBL19377220 | 0.86 | HSD17B10 (0.49) | NAMPTMLNRRORCCYP2C9CA12 | |
| SCHEMBL19377104 | 0.85 | POLB (0.40) | NAMPTMLNRCA12CA1CA2 | |
| SCHEMBL24800040 | 0.85 | MLNR (0.39) | NAMPTMLNRCYP2C9DRD2DRD3 | |
| SCHEMBL19377261 | 0.83 | CA12 (0.49) | NAMPTMLNRRORCCYP2D6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390355-B1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2022-12-28 | — | — | EP | disclosed |