Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24801169 | 0.86 | PKN1 (0.45) | PKN1PKN2PARP1PTGER4CD38 | |
| SCHEMBL29948229 | 0.86 | PKN1 (0.45) | PKN1PKN2PARP1PTGER4CD38 | |
| SCHEMBL24801179 | 0.84 | PKN1 (0.41) | PKN1PKN2PARP1PTGER4TYK2 | |
| SCHEMBL29948273 | 0.83 | PKN1 (0.43) | PKN1PKN2PARP1PTGER4TYK2 | |
| SCHEMBL29948161 | 0.83 | PKN1 (0.43) | PKN1PKN2PARP1PTGER4BRD4 | |
| SCHEMBL23529310 | 0.83 | PKN1 (0.43) | PKN1PKN2PARP1PTGER4TYK2 | |
| SCHEMBL24801168 | 0.83 | PKN1 (0.43) | PKN1PKN2PARP1PTGER4BRD4 | |
| SCHEMBL24800778 | 0.80 | PKN1 (0.38) | PKN1PKN2PARP1PTGER4TYK2 | |
| SCHEMBL24801182 | 0.80 | TYK2 (0.38) | PKN1PKN2PARP1PTGER4TYK2 | |
| SCHEMBL30159588 | 0.80 | TYK2 (0.38) | PKN1PKN2PARP1PTGER4TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266711-A1 | SUBSTITUTED AMIDOBENZIMIDAZOLE DIMERS AS STING MODULATORS | Aculeus Therapeutics Pty Ltd (AU) | 2022-12-29 | — | — | WO | disclosed |