Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23529310 | 1.00 | PKN1 (0.43) | PKN1PKN2PARP1CFTRPTGER4 | |
| SCHEMBL23529317 | 0.87 | PKN1 (0.38) | PKN1PKN2PARP1PTGER4CD38 | |
| SCHEMBL29948142 | 0.87 | PKN1 (0.38) | PKN1PKN2PARP1PTGER4CD38 | |
| SCHEMBL29948229 | 0.85 | PKN1 (0.45) | PKN1PKN2PARP1PTGER4CD38 | |
| SCHEMBL24801169 | 0.85 | PKN1 (0.45) | PKN1PKN2PARP1PTGER4CD38 | |
| SCHEMBL24801179 | 0.83 | PKN1 (0.41) | PKN1PKN2PARP1PTGER4IDH1 | |
| SCHEMBL24801176 | 0.83 | PKN1 (0.41) | PKN1PKN2PARP1PTGER4CD38 | |
| SCHEMBL29948161 | 0.83 | PKN1 (0.43) | PKN1PKN2PARP1PTGER4 | |
| SCHEMBL24801168 | 0.83 | PKN1 (0.43) | PKN1PKN2PARP1PTGER4 | |
| SCHEMBL24801182 | 0.79 | TYK2 (0.38) | PKN1PKN2PARP1PTGER4IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981265-B | Compounds of formula (I) | CTXT私人有限公司 | 2025-01-03 | — | — | CN | disclosed |
| WO-2022266711-A1 | SUBSTITUTED AMIDOBENZIMIDAZOLE DIMERS AS STING MODULATORS | Aculeus Therapeutics Pty Ltd (AU) | 2022-12-29 | — | — | WO | disclosed |
| EP-4077318-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2022-10-26 | — | — | EP | disclosed |