Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 3/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.32 |
| ▸ | STARD10 | Q9Y365 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24801232 | 0.93 | IDH1 (0.35) | MLNRITGB1ITGA4ITGB7NAMPT | |
| SCHEMBL19377342 | 0.93 | MLNR (0.36) | MLNRGHSRITGB1ITGA4NAMPT | |
| SCHEMBL19377071 | 0.87 | MLNR (0.39) | MLNRGHSRITGB1ITGA4IDH1 | |
| SCHEMBL19377070 | 0.87 | MLNR (0.39) | MLNRGHSRITGB1ITGA4IDH1 | |
| SCHEMBL19377656 | 0.84 | MLNR (0.46) | MLNR | |
| SCHEMBL19377658 | 0.84 | MLNR (0.46) | MLNR | |
| SCHEMBL19377369 | 0.84 | MLNR (0.46) | MLNR | |
| SCHEMBL19377366 | 0.84 | MLNR (0.46) | MLNR | |
| SCHEMBL19377152 | 0.83 | MLNR (0.35) | MLNRGHSRITGB1ITGA4IDH1 | |
| SCHEMBL19377417 | 0.82 | GHSR (0.38) | MLNRGHSRNAMPTIDH1PCTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390355-B1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2022-12-28 | — | — | EP | disclosed |