Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 8/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26003250 | 0.87 | LRRK2 (0.37) | FFAR4IDH1EPHX2 | |
| SCHEMBL31312913 | 0.87 | LRRK2 (0.37) | FFAR4IDH1EPHX2 | |
| SCHEMBL24206805 | 0.87 | FFAR4 (0.42) | FFAR4CHRM2CHRM4 | |
| SCHEMBL28899818 | 0.87 | LTA4H (0.39) | FFAR4LTA4HCHRM2ACACBCHRM4 | |
| SCHEMBL25957189 | 0.87 | LTA4H (0.39) | FFAR4LTA4HCHRM2ACACBCHRM4 | |
| SCHEMBL24207600 | 0.86 | FFAR4 (0.45) | FFAR4IDH1 | |
| SCHEMBL25339547 | 0.85 | NOTUM (0.44) | — | |
| SCHEMBL25339552 | 0.85 | NOTUM (0.44) | — | |
| SCHEMBL30511792 | 0.83 | MYC (0.38) | — | |
| SCHEMBL26171398 | 0.83 | S1PR5 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268052-A9 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2022268052-A1 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BEIGENE, LTD. (KY) | 2022-12-29 | — | — | WO | disclosed |