Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.45 |
| ▸ | SLC13A2 | Q13183 | 1/20 | 0.45 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24804840 | 0.85 | GAA (0.44) | POLBHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30148645 | 0.84 | POLB (0.40) | POLBHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL24804839 | 0.83 | POLB (0.39) | POLBHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL24802483 | 0.82 | POLB (0.48) | POLBHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29180831 | 0.81 | HPGD (0.39) | POLBHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30148681 | 0.79 | GRIN1 (0.38) | POLBHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30148709 | 0.77 | NR1I3 (0.38) | POLBALDH1A1KDM4EGRIN1GRIN2B | |
| SCHEMBL24804845 | 0.77 | NR1I3 (0.38) | POLBALDH1A1KDM4EGRIN1GRIN2B | |
| SCHEMBL24804852 | 0.76 | POLB (0.36) | POLBHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30148571 | 0.76 | POLB (0.36) | POLBHPGDSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268209-A1 | DERIVATIVE HAVING PYRIMIDINE-FUSED CYCLIC STRUCTURE, AND USE THEREOF | 四川汇宇制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |