Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24802434 | 0.87 | MAPK8 (0.48) | MEN1KMT2AACHEPOLBCYP3A4 | |
| SCHEMBL24802541 | 0.83 | POLB (0.59) | MEN1KMT2APOLBCYP3A4ALDH1A1 | |
| SCHEMBL19181005 | 0.83 | GAA (0.57) | MEN1KMT2APOLBCYP3A4CYP1A2 | |
| SCHEMBL30772170 | 0.83 | GAA (0.57) | MEN1KMT2APOLBCYP3A4CYP1A2 | |
| SCHEMBL12257910 | 0.81 | HSD17B10 (0.56) | MEN1KMT2AACHETSHRSLC13A5 | |
| SCHEMBL1922665 | 0.81 | CYP3A4 (0.62) | MEN1KMT2AACHECYP3A4SLC13A5 | |
| Hydrochloric Acid SCHEMBL30148629 | 0.81 | GAA (0.56) | MEN1KMT2APOLBCYP3A4CYP1A2 | |
| SCHEMBL2064203 | 0.81 | DPP4 (0.48) | MEN1KMT2AACHEALDH1A1L3MBTL1 | |
| SCHEMBL24804875 | 0.80 | NR1H4 (0.44) | MEN1KMT2APOLBCYP3A4CYP1A2 | |
| SCHEMBL3619308 | 0.80 | NR1H4 (0.50) | MEN1KMT2APOLBCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268209-A1 | DERIVATIVE HAVING PYRIMIDINE-FUSED CYCLIC STRUCTURE, AND USE THEREOF | 四川汇宇制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |