Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24802505 | 0.88 | HSD17B10 (0.44) | POLBMEN1KMT2ATSHRKDM4E | |
| SCHEMBL30772197 | 0.88 | HSD17B10 (0.44) | POLBMEN1KMT2ATSHRKDM4E | |
| Hydrochloric Acid SCHEMBL30148685 | 0.87 | MEN1 (0.43) | POLBMEN1KMT2ATSHRKDM4E | |
| SCHEMBL24802459 | 0.80 | MEN1 (0.45) | POLBMEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL24802541 | 0.79 | POLB (0.59) | POLBMEN1KMT2AKDM4ECYP3A4 | |
| SCHEMBL19181005 | 0.79 | GAA (0.57) | POLBMEN1KMT2ATSHRKDM4E | |
| SCHEMBL30772170 | 0.79 | GAA (0.57) | POLBMEN1KMT2ATSHRKDM4E | |
| Hydrochloric Acid SCHEMBL30148629 | 0.78 | GAA (0.56) | POLBMEN1KMT2ATSHRKDM4E | |
| SCHEMBL29180845 | 0.78 | KDM4E (0.44) | NR1H4POLBTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL14267817 | 0.77 | MAPT (0.44) | NR1H4MEN1KMT2ATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268209-A1 | DERIVATIVE HAVING PYRIMIDINE-FUSED CYCLIC STRUCTURE, AND USE THEREOF | 四川汇宇制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |