SCHEMBL24802460

SCHEMBL24802460

COc1ncc(I)cc1CC#N

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24802484 0.81 SLC13A5 (0.44) PIK3CG
SCHEMBL21408261 0.80 CYP2C9 (0.38) PIK3CG
SCHEMBL30434407 0.80 CYP2C9 (0.38) PIK3CG
SCHEMBL4393816 0.77 SLC13A5 (0.31)
SCHEMBL15053307 0.74 GAA (0.40) PIK3CG
SCHEMBL25685882 0.70 MAPT (0.35)
SCHEMBL5780520 0.69 APLNR (0.44)
SCHEMBL1020594 0.69 RECQL (0.35)
SCHEMBL23663186 0.67 S100A9 (0.36)
SCHEMBL21516797 0.67 PIK3CA (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022268209-A1 DERIVATIVE HAVING PYRIMIDINE-FUSED CYCLIC STRUCTURE, AND USE THEREOF 四川汇宇制药股份有限公司 2022-12-29 WO disclosed