⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28377521 | 0.82 | MAOB (0.39) | — | |
| SCHEMBL29158584 | 0.81 | TAAR1 (0.41) | — | |
| SCHEMBL1442990 | 0.79 | — | — | |
| SCHEMBL9746120 | 0.78 | — | — | |
| SCHEMBL30506 | 0.78 | — | — | |
| SCHEMBL27992203 | 0.78 | — | — | |
| SCHEMBL5541959 | 0.78 | — | — | |
| SCHEMBL27663911 | 0.76 | — | — | |
| SCHEMBL27663912 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL28198042 | 0.76 | SLC1A3 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678342-A1 | N-SUBSTITUTED OXAZINOPTERIDINES AND OXAZINOPTERIDINONES | Takeda Pharmaceutical Company Limited (JP) | 2014-01-01 | — | — | EP | claimed |
| WO-2012148548-A1 | N-SUBSTITUTED OXAZINOPTERIDINES AND OXAZINOPTERIDINONES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-11-01 | — | — | WO | claimed |
| US-20250282731-A1 | SUBSTITUTED 3-DIALKYLAMINOMETHYL-PIPERIDIN-4-YL-BENZAMIDES AND METHODS OF MAKING AND USING SAME | MEBIAS DISCOVERY INC (US) | 2025-09-11 | — | — | US | disclosed |
| CN-110256404-B | Diene compound with insecticidal activity, preparation and application thereof | 华东理工大学 | 2025-05-27 | — | — | CN | disclosed |
| US-12162837-B2 | Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same | MEBIAS DISCOVERY, INC. (US) | 2024-12-10 | — | — | US | disclosed |
| WO-2024182778-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| EP-3570838-B1 | SUBSTITUTED 3-DIALKYLAMINOMETHYL-PIPERIDIN-4-YL-BENZAMIDES AND METHODS OF MAKING AND USING SAME | MEBIAS DISCOVERY INC (US) | 2024-06-05 | — | — | EP | disclosed |
| US-20240043387-A1 | SUBSTITUTED 3-DIALKYLAMINOMETHYL-PIPERIDIN-4-YL-BENZAMIDES AND METHODS OF MAKING AND USING SAME | MEBIAS DISCOVERY INC (US) | 2024-02-08 | — | — | US | disclosed |
| EP-3880659-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2024-01-03 | — | — | EP | disclosed |
| CN-116751156-A | Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using the same | 梅比斯发现公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-110392571-B | Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using the same | 梅比斯发现公司 | 2023-07-04 | — | — | CN | disclosed |
| US-5731452-A | 7-thiaprostaglandins and method of production thereof | TEIJIN LIMITED (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0695741-A1 | 7-THIAPROSTAGLANDINS AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1996-02-07 | — | — | EP | disclosed |
| US-5368876-A | Flavoring and perfume compositions and flavored and perfumed products which contain one or more substituted thiophenes | NAARDEN-INTERNATIONAL N.V. (NL) | 1994-11-29 | — | — | US | disclosed |
| US-5196224-A | Substituted thiophenes, and flavoring and perfume compositions and flavored and perfumed products which contain one or more substituted thiophenes | NAARDEN-INTERNATIONAL N.V. (NL) | 1993-03-23 | — | — | US | disclosed |
| EP-0219146-B1 | SUBSTITUTED THIOPHENES, FLAVOURING AND PERFUMING COMPOSITIONS, PERFUMED PRODUCTS CONTAINING THEM | NAARDEN INTERNATIONAL N.V. (NL) | 1990-10-31 | — | — | EP | disclosed |
| EP-0219146-A1 | Substituted thiophenes, flavouring and perfuming compositions, perfumed products containing them | NAARDEN INTERNATIONAL N.V. (NL) | 1987-04-22 | — | — | EP | disclosed |
| US-4292427-A | BACTERICIDES | MERCK & CO., INC. (US) | 1981-09-29 | — | — | US | disclosed |
| US-4210750-A | BY TREATMENT OF 3-HYDROXYMETHYL DERIVATIVE WITH TRIFLUOROACETYL ISOCYANATE | MERCK & CO., INC. (US) | 1980-07-01 | — | — | US | disclosed |
| US-4173703-A | Preparation of carbamates | MERCK & CO., INC. (US) | 1979-11-06 | — | — | US | disclosed |