⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28198042 | 0.98 | SLC1A3 (0.46) | — | |
| SCHEMBL27488641 | 0.80 | TAAR1 (0.48) | — | |
| SCHEMBL248034 | 0.78 | — | — | |
| SCHEMBL5535967 | 0.77 | TAAR1 (0.46) | — | |
| SCHEMBL5541802 | 0.76 | TAAR1 (0.44) | — | |
| SCHEMBL5544151 | 0.74 | TAAR1 (0.43) | — | |
| SCHEMBL5541464 | 0.74 | TAAR1 (0.43) | — | |
| SCHEMBL11392894 | 0.74 | CA2 (0.39) | — | |
| SCHEMBL1138837 | 0.71 | — | — | |
| SCHEMBL1145679 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085564-B | A kind of synthetic method of pesticide Silthiopham | 杭州师范大学 | 2019-05-14 | — | — | CN | claimed |
| CN-105745214-B | Tricyclic piperidine compounds | 埃科特莱茵药品有限公司 | 2019-02-19 | — | — | CN | claimed |
| EP-0657166-B1 | Combination containing a quinoxaline and a nucleoside | AVENTIS PHARMA GMBH (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-0509398-B1 | Quinoxalines, process for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2001-09-19 | — | — | EP | claimed |
| EP-0977570-A1 | QUINOXALINE IN TRIPLE COMBINATION WITH PROTEASE INHIBITORS AND REVERSE TRANSCRIPTASE INHIBITORS AS MEDICINES FOR TREATING AIDS | BAYER AG (DE) | 2000-02-09 | — | — | EP | claimed |
| WO-1998032442-A1 | QUINOXALINE IN TRIPLE COMBINATION WITH PROTEASE INHIBITORS AND REVERSE TRANSCRIPTASE INHIBITORS AS MEDICINES FOR TREATING AIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-30 | — | — | WO | claimed |
| EP-0728481-A2 | Use of quinoxaline and protease inhibitors in a composition for the treatment of AIDS and/or HIV infections | BAYER AG (DE) | 1996-08-28 | — | — | EP | claimed |
| EP-0509398-A1 | Quinoxalines, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-21 | — | — | EP | claimed |
| CN-114989155-B | 1,3, 4-oxadiazole thioether derivative, and preparation method and application thereof | 河北农业大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-114989155-A | 1,3, 4-oxadiazole thioether derivative and preparation method and application thereof | 河北农业大学 | 2022-09-02 | — | — | CN | disclosed |
| US-20210309619-A1 | ISOXAZOLIN-5-ONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-10-07 | — | — | US | disclosed |
| US-11109593-B2 | Isoxazolin-5-one derivative and herbicide containing same as active ingredient | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-09-07 | — | — | US | disclosed |
| EP-3828176-A1 | ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | Hokko Chemical Industry Co., Ltd. (JP) | 2021-06-02 | — | — | EP | disclosed |
| US-20200267985-A1 | ISOXAZOLIN-5-ONE DERIVATIVE AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-08-27 | — | — | US | disclosed |
| EP-0509398-B1 | Quinoxalines, process for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2001-09-19 | — | — | EP | disclosed |
| EP-0977570-A1 | QUINOXALINE IN TRIPLE COMBINATION WITH PROTEASE INHIBITORS AND REVERSE TRANSCRIPTASE INHIBITORS AS MEDICINES FOR TREATING AIDS | BAYER AG (DE) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998032442-A1 | QUINOXALINE IN TRIPLE COMBINATION WITH PROTEASE INHIBITORS AND REVERSE TRANSCRIPTASE INHIBITORS AS MEDICINES FOR TREATING AIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-30 | — | — | WO | disclosed |
| EP-0728481-A2 | Use of quinoxaline and protease inhibitors in a composition for the treatment of AIDS and/or HIV infections | BAYER AG (DE) | 1996-08-28 | — | — | EP | disclosed |
| EP-0657166-A1 | Combination containing a quinoxaline and a nucleoside | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-14 | — | — | EP | disclosed |
| EP-0509398-A1 | Quinoxalines, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-21 | — | — | EP | disclosed |