Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 15/20 | 0.44 |
| ▸ | FEN1 | P39748 | 15/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24805183 | 0.88 | ALOX5AP (0.40) | ALOX5APFEN1FYNTGFBR1ACVR1 | |
| SCHEMBL24805880 | 0.82 | ALOX5AP (0.43) | ALOX5APFEN1JAK2JAK1TYK2 | |
| SCHEMBL24804120 | 0.82 | ALOX5AP (0.39) | ALOX5APFEN1FYNTGFBR1ACVR1 | |
| SCHEMBL24804125 | 0.81 | ALOX5AP (0.36) | ALOX5APFEN1FYNTGFBR1ACVR1 | |
| SCHEMBL24804121 | 0.81 | ALOX5AP (0.36) | ALOX5APFEN1FYNTGFBR1ACVR1 | |
| SCHEMBL24804118 | 0.80 | ALOX5AP (0.40) | ALOX5APFEN1FYN | |
| SCHEMBL24805174 | 0.80 | ALOX5AP (0.41) | ALOX5APFEN1JAK2JAK1TYK2 | |
| SCHEMBL24805893 | 0.78 | ALOX5AP (0.37) | ALOX5APFEN1FYNTGFBR1ACVR1 | |
| SCHEMBL24498490 | 0.76 | ALOX5AP (0.43) | ALOX5APFEN1FYNTYK2 | |
| SCHEMBL24899855 | 0.76 | FYN (0.44) | ALOX5APFEN1FYNTGFBR1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268119-A1 | SULFOXIMINE COMPOUND AND USE THEREOF | 南京明德新药研发有限公司 | 2022-12-29 | — | — | WO | disclosed |