Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 4/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.43 |
| ▸ | FEN1 | P39748 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23925790 | 0.77 | KDM1A (0.43) | FYNALOX5APFEN1TGFBR1 | |
| SCHEMBL29740023 | 0.77 | KDM1A (0.43) | FYNALOX5APFEN1TGFBR1 | |
| SCHEMBL24804116 | 0.76 | ALOX5AP (0.44) | FYNALOX5APFEN1TGFBR1ACVR1 | |
| SCHEMBL26099039 | 0.75 | MAPK1 (0.47) | ALOX5APFEN1TGFBR1 | |
| SCHEMBL30392625 | 0.75 | MAPK1 (0.47) | ALOX5APFEN1TGFBR1 | |
| SCHEMBL23980129 | 0.73 | TYK2 (0.44) | FYNALOX5APFEN1TGFBR1ACVR1 | |
| SCHEMBL24498490 | 0.73 | ALOX5AP (0.43) | FYNALOX5APFEN1TYK2 | |
| SCHEMBL27295955 | 0.72 | SMN1; SMN2 (0.47) | TGFBR1JAK2JAK1TYK2JAK3 | |
| SCHEMBL24899738 | 0.72 | ALOX5AP (0.36) | FYNALOX5APFEN1 | |
| SCHEMBL31106622 | 0.71 | ALOX5AP (0.49) | FYNALOX5APFEN1TGFBR1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284869-A1 | SULFUR/PHOSPHORUS-CONTAINING ARYL COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |