Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 14/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476644 | 0.93 | TACR3 (0.55) | TACR3SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL2478849 | 0.91 | TACR3 (0.51) | TACR3SLC6A3SLC6A2SLC6A4TACR2 | |
| SCHEMBL2482572 | 0.89 | TACR3 (0.63) | TACR3TACR2TACR1 | |
| SCHEMBL2478511 | 0.88 | TACR3 (0.51) | TACR3TACR2TACR1 | |
| SCHEMBL2477546 | 0.87 | TACR3 (0.55) | TACR3SLC6A3SLC6A2SLC6A4TACR2 | |
| SCHEMBL2476832 | 0.81 | TACR3 (0.61) | TACR3TACR2TACR1 | |
| SCHEMBL2479387 | 0.80 | TACR3 (0.67) | TACR3TACR2TACR1 | |
| SCHEMBL2478297 | 0.80 | TACR3 (0.67) | TACR3TACR2TACR1 | |
| SCHEMBL2477496 | 0.78 | TACR3 (0.72) | TACR3TACR2TACR1 | |
| SCHEMBL2475515 | 0.78 | TACR3 (0.72) | TACR3TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656349-B1 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2011-10-12 | — | — | EP | disclosed |