Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 10/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474144 | 0.94 | HDAC1 (0.49) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL3834514 | 0.92 | HDAC1 (0.51) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2471256 | 0.92 | UTS2R (0.58) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2471332 | 0.91 | HDAC1 (0.50) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL3835404 | 0.91 | HDAC1 (0.59) | UTS2RHDAC1ROCK2ROCK1HDAC3 | |
| SCHEMBL3834328 | 0.91 | HDAC1 (0.52) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2504353 | 0.89 | UTS2R (0.65) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL3832758 | 0.86 | UTS2R (0.49) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2478630 | 0.86 | HDAC1 (0.56) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL3834409 | 0.86 | UTS2R (0.49) | UTS2RHDAC1HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-B1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |