⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24807305 | 0.90 | — | — | |
| SCHEMBL25061872 | 0.89 | — | — | |
| SCHEMBL24809934 | 0.87 | AR (0.31) | — | |
| SCHEMBL24807307 | 0.85 | MAT2A (0.40) | — | |
| SCHEMBL24808402 | 0.85 | — | — | |
| SCHEMBL24807129 | 0.83 | TNIK (0.31) | — | |
| SCHEMBL30095576 | 0.82 | — | — | |
| SCHEMBL24807320 | 0.82 | — | — | |
| SCHEMBL25061942 | 0.82 | — | — | |
| SCHEMBL30095785 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359389-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117480155-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-30 | — | — | CN | disclosed |
| US-20230060004-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-23 | — | — | US | disclosed |
| WO-2022271677-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022271677-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |