SCHEMBL24809056

SCHEMBL24809056

Cc1cc(C)cc(C(=O)Nc2ccc(Br)c3ccccc23)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 3/20 0.60
EPHX1 P07099 2/20 0.53
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
MAPT P10636 4/20 0.52
GAA P10253 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
POLB P06746 1/20 0.48
TP53 P04637 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HDAC1 Q13547 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24810184 0.91 KMT2A (0.53) RXFP1EPHX1MEN1KMT2AMAPT
SCHEMBL29124130 0.83 EPHX1 (0.73) RXFP1EPHX1MEN1KMT2AMAPT
SCHEMBL24807592 0.78 SMN1; SMN2 (0.46) RXFP1MEN1KMT2AMAPTKDM4E
SCHEMBL24170181 0.78 RXFP1 (0.62) RXFP1EPHX1MEN1KMT2AMAPT
SCHEMBL30900909 0.78 MEN1 (0.63) RXFP1EPHX1MEN1KMT2AMAPT
SCHEMBL24807651 0.78 HDAC1 (0.48) RXFP1EPHX1MEN1KMT2AMAPT
SCHEMBL1978079 0.77 RXFP1 (0.71) RXFP1EPHX1MEN1KMT2AMAPT
SCHEMBL24809341 0.76 S1PR4 (0.46) RXFP1MEN1KMT2AMAPTPOLB
SCHEMBL6835642 0.76 RXFP1 (1.00) RXFP1EPHX1MEN1KMT2AMAPT
SCHEMBL30064828 0.76 RXFP1 (1.00) RXFP1EPHX1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022267941-A1 ORGANOMETALLIC IRIDIUM COMPOUND 广东阿格蕾雅光电材料有限公司 2022-12-29 WO disclosed