Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24807592 | 0.86 | SMN1; SMN2 (0.46) | THRBRXFP1TP53SMN1; SMN2MEN1 | |
| SCHEMBL24810184 | 0.82 | KMT2A (0.53) | THRBRXFP1TP53SMN1; SMN2MEN1 | |
| SCHEMBL24809056 | 0.76 | RXFP1 (0.60) | RXFP1TP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24809363 | 0.68 | DHODH (0.49) | THRBMEN1KMT2APOLBMAPT | |
| SCHEMBL12581572 | 0.67 | GRM5 (0.57) | S1PR4THRBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30900918 | 0.67 | MAPT (0.47) | RXFP1TP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1817366 | 0.66 | GRM5 (0.60) | S1PR4TP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25944931 | 0.66 | KCNJ11 (0.59) | RXFP1MEN1KMT2APOLBMAPT | |
| SCHEMBL2917557 | 0.65 | PKM (0.60) | S1PR4THRBSMN1; SMN2 | |
| SCHEMBL9523014 | 0.65 | S1PR4 (0.69) | S1PR4SMN1; SMN2KMT2APOLBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022267941-A1 | ORGANOMETALLIC IRIDIUM COMPOUND | 广东阿格蕾雅光电材料有限公司 | 2022-12-29 | — | — | WO | disclosed |