Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 12/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30050974 | 1.00 | BRAF (0.34) | BRAFDPP4ERBB2 | |
| SCHEMBL24807693 | 0.84 | DPP4 (0.34) | DPP4ERBB2 | |
| SCHEMBL31693489 | 0.84 | DPP4 (0.34) | DPP4ERBB2 | |
| Hydrochloric Acid SCHEMBL31257322 | 0.83 | DPP4 (0.33) | DPP4ERBB2 | |
| SCHEMBL30050420 | 0.82 | GRM5 (0.42) | BRAFERBB2 | |
| SCHEMBL24807701 | 0.82 | GRM5 (0.42) | BRAFERBB2 | |
| SCHEMBL24569478 | 0.82 | KMT2A (0.44) | ERBB2 | |
| SCHEMBL29887844 | 0.82 | KMT2A (0.44) | ERBB2 | |
| SCHEMBL30049938 | 0.82 | ALDH1A1 (0.36) | BRAF | |
| SCHEMBL31257309 | 0.81 | DPP4 (0.32) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940425-A | HER2 mutation inhibitors | 阿雷生物药品公司 | 2024-04-26 | — | — | CN | disclosed |
| US-20230041385-A1 | HER2 MUTATION INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2023-02-09 | — | — | US | disclosed |
| WO-2022269531-A1 | HER2 MUTATION INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230041385-A1 | HER2 MUTATION INHIBITORS | ERBB2, EGFR, ERBB3 | BRAF 24/4885DPP4 4119/4885ERBB2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.