Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tenofovir Diphosphate SCHEMBL14354588 | 1.00 | CYP3A4 (0.77) | CYP3A4CYP2D6 | |
| Tenofovir Diphosphate SCHEMBL29395812 | 1.00 | CYP3A4 (0.77) | CYP3A4CYP2D6 | |
| Tenofovir Diphosphate SCHEMBL29466912 | 1.00 | CYP3A4 (0.77) | CYP3A4CYP2D6 | |
| SCHEMBL14440381 | 0.96 | CYP3A4 (0.80) | CYP3A4CYP2D6 | |
| SCHEMBL24809662 | 0.96 | CYP3A4 (0.80) | CYP3A4CYP2D6 | |
| SCHEMBL19600198 | 0.94 | CYP3A4 (0.77) | CYP3A4CYP2D6 | |
| SCHEMBL20313254 | 0.92 | CYP3A4 (0.74) | CYP3A4CYP2D6 | |
| SCHEMBL13394187 | 0.91 | CYP3A4 (0.75) | CYP3A4CYP2D6 | |
| SCHEMBL20321881 | 0.90 | CYP3A4 (0.71) | CYP3A4CYP2D6 | |
| Tenofovir Anhydrous SCHEMBL400717 | 0.89 | CYP3A4 (0.91) | CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271880-A1 | METHODS OF TREATING MEDICAL CONDITIONS AND INHIBITING LINE1 REVERSE TRANSCRIPTASE USING A SUBSTITUTED ADENINYL-PROPYLOXY PHOSPHONIC ACID OR RELATED COMPOUND | ROME THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |