Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22567700 | 0.86 | EPHX2 (0.33) | ALDH1A1 | |
| SCHEMBL367170 | 0.84 | TDP1 (0.42) | ALDH1A1 | |
| SCHEMBL21848627 | 0.84 | TDP1 (0.42) | ALDH1A1 | |
| SCHEMBL641988 | 0.84 | TDP1 (0.42) | ALDH1A1 | |
| SCHEMBL1477656 | 0.84 | TDP1 (0.42) | ALDH1A1 | |
| SCHEMBL93743 | 0.84 | TDP1 (0.42) | ALDH1A1 | |
| SCHEMBL26763455 | 0.83 | MEN1 (0.39) | — | |
| SCHEMBL24810931 | 0.83 | EPHX1 (0.38) | ALDH1A1 | |
| SCHEMBL7705689 | 0.82 | TDP1 (0.40) | ALDH1A1 | |
| Water SCHEMBL1825839 | 0.82 | TDP1 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220409747-A1 | FIBROBLAST ACTIVATION PROTEIN (FAP)-TARGETED IMAGING AND THERAPY OF CANCERS AND OTHER FIBROTIC AND INFLAMMATORY DISEASES | PURDUE RESEARCH FOUNDATION | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220409747-A1 | FIBROBLAST ACTIVATION PROTEIN (FAP)-TARGETED IMAGING AND THERAPY OF CANCERS AND OTHER FIBROTIC AND INFLAMMATORY DISEASES | FAP, FIBP, FGFR1 | ALDH1A1 1661/4885OPRM1 4865/4885OPRL1 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.