SCHEMBL24812420

SCHEMBL24812420

CC(C)C(=O)n1cc(C(C)C)nn1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25791768 0.78 KDM4E (0.31)
SCHEMBL24812415 0.77 SMN1; SMN2 (0.33) ALDH1A1GAA
SCHEMBL22326632 0.75 MAPK1 (0.36) ALDH1A1
SCHEMBL24520764 0.74
SCHEMBL16171674 0.69 NTRK1 (0.38)
SCHEMBL19370410 0.69
SCHEMBL24777725 0.68 ALDH1A1 (0.44) ALDH1A1
SCHEMBL25834818 0.67 NR1H4 (0.36)
SCHEMBL22515608 0.67 IDO1 (0.33)
SCHEMBL23581668 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022272133-A2 PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS Stablix, Inc. (US) 2022-12-29 WO disclosed