Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 10/20 | 0.78 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.78 |
| ▸ | NOTUM | Q6P988 | 10/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25802756 | 1.00 | KEAP1 (0.78) | KEAP1NFE2L2NOTUM | |
| SCHEMBL24812743 | 0.92 | KEAP1 (0.87) | KEAP1NFE2L2NOTUM | |
| SCHEMBL25802758 | 0.90 | KEAP1 (0.82) | KEAP1NFE2L2NOTUM | |
| SCHEMBL24812642 | 0.90 | KEAP1 (0.82) | KEAP1NFE2L2NOTUM | |
| SCHEMBL25832152 | 0.89 | KEAP1 (0.81) | KEAP1NFE2L2NOTUM | |
| SCHEMBL17599452 | 0.88 | KEAP1 (1.00) | KEAP1NFE2L2NOTUM | |
| SCHEMBL29584677 | 0.88 | KEAP1 (1.00) | KEAP1NFE2L2NOTUM | |
| SCHEMBL17599491 | 0.88 | KEAP1 (1.00) | KEAP1NFE2L2NOTUM | |
| SCHEMBL17599442 | 0.88 | KEAP1 (1.00) | KEAP1NFE2L2NOTUM | |
| SCHEMBL24811431 | 0.88 | KEAP1 (0.85) | KEAP1NFE2L2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |